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No not that E. According to this chat transcript, my second favorite comic strip (after The Boondocks) Pearls Before Swine began life as an online comic strip, then later picked up by a synidicate. I wonder if this will be trend in the future, where syndicates pick up successful online strips. Maybe someday we'll see Diesel Sweeties tucked away in the pages of The Daily Oklahoman.
I thought this comic from the other day was particularly amusing, but I wondered why it was set at an anti-globalization protest, rather than, say, an anti-war action. In the transcript artist Stephan Pastis says that the synidicate is re-running the greatest hits from Pearls online-only days, so maybe this is an older strip.